ADRB1 antibody (C-Term)

Catalog No. ABIN7482648

The Rabbit Polyclonal anti-ADRB1 antibody (ABIN7482648) specifically detects ADRB1 in WB. The antibody is reactive with Human and Rabbit samples.

Quick Overview for ADRB1 antibody (C-Term) (ABIN7482648)

Target: ADRB1 (Adrenergic, beta-1-, Receptor (ADRB1))

Reactivity: Human, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADRB1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ADRB1 Antibody

Binding Specificity: C-Term

Sequence: SDDDDDDVVG ATPPARLLEP WAGCNGGAAA DSDSSLDEPC RPGFASESKV

Predicted Reactivity: Human: 100%, Rabbit: 91%

Characteristics: This is a rabbit polyclonal antibody against ADRB1. It was validated on Western Blot.

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human ADRB1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ADRB1

Target: ADRB1 (Adrenergic, beta-1-, Receptor (ADRB1))

Alternative Name: ADRB1

Background: ADRB1 is a beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity. It mediates Ras activation through G(s)-alpha- and cAMP-mediated signaling.

Alias Symbols: ADRB1R, B1AR, BETA1AR, RHR

Protein Interaction Partner: GPRASP1, GPRASP2, SNTA1, ARRB2, ARRB1, MAGI2, DLG4, GRB2, ADRA2A, MAGI3, DLGAP2, GOPC, GIPC1, SH3GL2, SH3GL3, DLG1, NOS1,

Protein Size: 477

Gene ID: 153

NCBI Accession: NM_000684, NP_000675

UniProt: P08588

Pathways: cAMP Metabolic Process, Cellular Glucan Metabolic Process, Regulation of Muscle Cell Differentiation, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Brown Fat Cell Differentiation