AXIN2 antibody (N-Term)

Catalog No. ABIN5515390

Product Details anti-AXIN2 Antibody

Target: AXIN2 (Axin 2 (AXIN2))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Rabbit, Guinea Pig, Dog, Cow, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AXIN2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: FRTFLEREKC VDTLDFWFAC NGFRQMNLKD TKTLRVAKAI YKRYIENNSI

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against AXIN2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human AXIN2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for AXIN2

Target: AXIN2 (Axin 2 (AXIN2))

Alternative Name: AXIN2 (AXIN2 Products)

Synonyms: AXIL antibody, ODCRCS antibody, axil antibody, wu:fb37c08 antibody, zgc:111942 antibody, axin-2 antibody, xarp antibody, MGC81576 antibody, arp-A antibody, axin2 antibody, Axi1 antibody, Axil antibody, Conductin antibody, axin 2 antibody, axin 2 (conductin, axil) antibody, axin 2 (conductin, axil) S homeolog antibody, AXIN2 antibody, axin2 antibody, axin2.S antibody, Axin2 antibody

Background: AXIN2 is an inhibitor of the Wnt signaling pathway. It down-regulates beta-catenin. It probably facilitate the phosphorylation of beta- catenin and APC by GSK3B.

Alias Symbols: AXIN2,

Protein Interaction Partner: FBXW11, GSK3B, GSK3A, UBC, CDC20, AXIN1, KDM5B, ANKRD6, SMAD3, CSNK1E, APC, CTNNB1, APC2, ESR1,

Protein Size: 843

Gene ID: 8313

NCBI Accession: NP_004646

UniProt: Q9Y2T1

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling