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CCAR1 antibody (C-Term)
CCAR1
Reactivity: Human, Mouse, Rat, Dog, Cow, Rabbit, Horse, Pig, Guinea Pig
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-CCAR1 Antibody
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Target
See all CCAR1 Antibodies
CCAR1
(Cell Division Cycle and Apoptosis Regulator 1 (CCAR1))
Binding Specificity
All epitopes for CCAR1 antibodies
C-Term
Reactivity
Human, Mouse, Rat, Dog, Cow, Rabbit, Horse, Pig, Guinea Pig
Host
All hosts for CCAR1 antibodies
Rabbit
Clonality
All clonalities for CCAR1 antibodies
Polyclonal
Conjugate
All conjugates for CCAR1 antibodies
This CCAR1 antibody is un-conjugated
Application
All applications for CCAR1 antibodies
Western Blotting (WB)
Sequence
YDPMEAEEAE DEEDDRDEEE MTKRDDKRDI NRYCKERPSK DKEKEKTQMI
Predicted Reactivity
Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 79%, Pig: 100%, Rabbit: 86%, Rat: 93%
Characteristics
This is a rabbit polyclonal antibody against CCAR1. It was validated on Western Blot.
Purification
Affinity purified
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of Human CCAR1
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for CCAR1
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Target
CCAR1
(Cell Division Cycle and Apoptosis Regulator 1 (CCAR1))
Alternative Name
CCAR1 (CCAR1 Products )
Synonyms
CCAR1 antibody, KIAA1967 antibody, ccar1 antibody, MGC81663 antibody, zehn1480 antibody, hm:zehn1480 antibody, si:dkey-85g17.2 antibody, RP11-437A18.1 antibody, CARP-1 antibody, 2610511G16Rik antibody, 9430036H15Rik antibody, Carp1 antibody, RGD1560358 antibody, cell division cycle and apoptosis regulator 1 antibody, cell division cycle and apoptosis regulator 1 L homeolog antibody, cell division cycle and apoptosis regulator protein 1 antibody, CCAR1 antibody, ccar1.L antibody, LOC5575286 antibody, ccar1 antibody, LOC409891 antibody, Ccar1 antibody
Background
CCAR1 associates with components of the Mediator and p160 coactivator complexes that play a role as intermediaries transducing regulatory signals from upstream transcriptional activator proteins to basal transcription machinery at the core promoter. It is recruited to endogenous nuclear receptor target genes in response to the appropriate hormone. It also functions as a p53 coactivator. It may thus play an important role in transcriptional regulation (By similarity). It may be involved in apoptosis signaling in the presence of the reinoid CD437. It apoptosis induction involves sequestration of 14-3-3 protein(s) and mediated altered expression of multiple cell cycle regulatory genes including MYC, CCNB1 and CDKN1A. And it plays a role in cell cycle progression and/or cell proliferation. Alias Symbols: CARP1, DIS Protein Interaction Partner: PIH1D3, GOLGA2, SUMO2, SUMO3, UBC, TP53, MDM2, U2AF2, CHERP, UBL4A, RBM10, RNF113A, HNRNPK, SMURF1, BARD1, SIRT7, SF3A2, Kif23, FYCO1, CASP10, SFN, YWHAQ, Protein Size: 1150
Gene ID
55749
NCBI Accession
NP_060707
UniProt
Q8IX12
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