DET1 antibody (N-Term)

Catalog No. ABIN5515416

This Rabbit Polyclonal antibody specifically detects DET1 in WB. It exhibits reactivity toward Human, Mouse, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Rat and Zebrafish (Danio rerio).

Quick Overview for DET1 antibody (N-Term) (ABIN5515416)

Target: DET1

Reactivity: Human, Mouse, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Rat, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DET1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DET1 Antibody

Binding Specificity: N-Term

Sequence: DCRCVIVGSA AYLPDEPHPP FFEVYRNSES VTPNPRSPLE DYSLHIIDLH

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against DET1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human DET1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DET1

Target: DET1

Alternative Name: DET1

Background: DET1 is a component of the E3 ubiquitin ligase DCX DET1-COP1 complex, which is required for ubiquitination and subsequent degradation of target proteins. The complex is involved in JUN ubiquitination and degradation.

Alias Symbols: -

Protein Interaction Partner: CUL4A, CUL4B, DDB1, RFWD2, HSP90AA1, DDA1, UBE2E3, PRMT5, UBE2E1, HSPA4, RBX1,

Protein Size: 561

Gene ID: 55070

NCBI Accession: NM_017996, NP_060466