VMP1 antibody (Middle Region)

Catalog No. ABIN5515450

The Rabbit Polyclonal anti-VMP1 antibody is suitable to detect VMP1 in samples from Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Saccharomyces cerevisiae and Zebrafish (Danio rerio). It has been validated for WB.

Quick Overview for VMP1 antibody (Middle Region) (ABIN5515450)

Target: VMP1 (Vacuole Membrane Protein 1 (VMP1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Saccharomyces cerevisiae, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VMP1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-VMP1 Antibody

Binding Specificity: Middle Region

Purpose: VMP1 Antibody - middle region

Sequence: SIISKVRIEA CMWGIGTAIG ELPPYFMARA ARLSGAEPDD EEYQEFEEML

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Yeast: 80%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against VMP1. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human VMP1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP49981-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for VMP1

Target: VMP1 (Vacuole Membrane Protein 1 (VMP1))

Alternative Name: VMP1

Background:

Background Information: VMP1 is a stress-induced protein that, when overexpressed, promotes formation of intracellular vacuoles followed by cell death. It may be involved in the cytoplasmic vacuolization of acinar cells during the early stage of acute pancreatitis. And it plays a role in the initial stages of the autophagic process through its interaction with BECN1 (By similarity). It involved in cell-cell adhesion. It plays an essential role in formation of cell junctions.

Gene Name: vacuole membrane protein 1

Alternative Symbols: EPG3, TANGO5, TMEM49

Protein Name: Vacuole membrane protein 1

Molecular Weight: 44kDa

Gene ID: 81671

NCBI Accession: NP_112200

UniProt: Q96GC9