GNAT1 antibody (N-Term)

Catalog No. ABIN5515492

The Rabbit Polyclonal anti-GNAT1 antibody is suitable to detect GNAT1 in samples from Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Sheep and Zebrafish (Danio rerio). It has been validated for WB.

Quick Overview for GNAT1 antibody (N-Term) (ABIN5515492)

Target: GNAT1 (Guanine Nucleotide Binding Protein (G Protein), alpha Transducing Activity Polypeptide 1 (GNAT1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Sheep, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GNAT1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GNAT1 Antibody

Binding Specificity: N-Term

Sequence: YSLEECLEFI AIIYGNTLQS ILAIVRAMTT LNIQYGDSAR QDDARKLMHM

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 77%, Rat: 100%, Sheep: 77%, Zebrafish: 85%

Characteristics: This is a rabbit polyclonal antibody against GNAT1. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human GNAT1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GNAT1

Target: GNAT1 (Guanine Nucleotide Binding Protein (G Protein), alpha Transducing Activity Polypeptide 1 (GNAT1))

Alternative Name: GNAT1

Background: Transducin is a 3-subunit guanine nucleotide-binding protein (G protein) which stimulates the coupling of rhodopsin and cGMP-phoshodiesterase during visual impulses. The transducin alpha subunits in rods and cones are encoded by separate genes. This gene encodes the alpha subunit in rods. This gene is also expressed in other cells, and has been implicated in bitter taste transduction in rat taste cells. Mutations in this gene result in autosomal dominant congenital stationary night blindness. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Alias Symbols: GNATR

Protein Interaction Partner: UBC, Haus1, RGS9, RGS16, F2R,

Protein Size: 350

Gene ID: 2779

NCBI Accession: NP_653082

UniProt: P11488

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, G-protein mediated Events, Phototransduction