PSMA7 antibody (C-Term)

Catalog No. ABIN5515527

This Rabbit Polyclonal antibody specifically detects PSMA7 in WB. It exhibits reactivity toward Human.

Quick Overview for PSMA7 antibody (C-Term) (ABIN5515527)

Target: PSMA7 (Proteasome Subunit alpha 7 (PSMA7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSMA7 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PSMA7 Antibody

Binding Specificity: C-Term

Sequence: VQSGGKNIEL AVMRRDQSLK ILNPEEIEKY VAEIEKEKEE NEKKKQKKAS

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human PSMA7

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PSMA7

Target: PSMA7 (Proteasome Subunit alpha 7 (PSMA7))

Alternative Name: PSMA7

Background: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the peptidase T1A family that functions as a 20S core alpha subunit. The encoded protein interacts with the hepatitis B virus X protein and plays a role in regulating hepatitis C virus internal ribosome entry site (IRES) activity, an activity essential for viral replication. The encoded protein also plays a role in the cellular stress response by regulating hypoxia-inducible factor-1alpha. A pseudogene of this gene is located on the long arm of chromosome 9.

Alias Symbols: C6, HSPC, RC6-1, XAPC7

Protein Size: 167

Gene ID: 5688

NCBI Accession: NM_002792, NP_002783

UniProt: O14818

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA