Kallikrein 1 antibody (N-Term)

Catalog No. ABIN5515562

The Rabbit Polyclonal anti-Kallikrein 1 antibody (ABIN5515562) specifically detects Kallikrein 1 in WB. The antibody is reactive with Human samples.

Quick Overview for Kallikrein 1 antibody (N-Term) (ABIN5515562)

Target: Kallikrein 1 (KLK1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Kallikrein 1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Kallikrein 1 Antibody

Binding Specificity: N-Term

Purpose: KLK1 Antibody - N-terminal region

Sequence: HNLFDDENTA QFVHVSESFP HPGFNMSLLE NHTRQADEDY SHDLMLLRLT

Characteristics: This is a rabbit polyclonal antibody against KLK1. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human KLK1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP76329-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Kallikrein 1

Target: Kallikrein 1 (KLK1)

Alternative Name: KLK1

Background:

Background Information: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. This protein is functionally conserved in its capacity to release the vasoactive peptide, Lys-bradykinin, from low molecular weight kininogen.

Alternative Symbols: hK1, KLKR, Klk6

Molecular Weight: 28 kDa

Gene ID: 3816

NCBI Accession: NP_002248

UniProt: P06870

Pathways: Complement System