POMP antibody (C-Term)

Catalog No. ABIN5515598

The Rabbit Polyclonal anti-POMP antibody (ABIN5515598) specifically detects POMP in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Horse and Zebrafish (Danio rerio) samples.

Quick Overview for POMP antibody (C-Term) (ABIN5515598)

Target: POMP (Proteasome Maturation Protein (POMP))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POMP antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-POMP Antibody

Binding Specificity: C-Term

Purpose: POMP Antibody - C-terminal region

Sequence: EFKAVQQVQR LPFLSSSNLS LDVLRGNDET IGFEDILNDP SQSEVMGEPH

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against POMP. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human POMP

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP56777-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for POMP

Target: POMP (Proteasome Maturation Protein (POMP))

Alternative Name: POMP

Background:

Background Information: The protein encoded by this gene is a molecular chaperone that binds 20S preproteasome components and is essential for 20S proteasome formation. The 20S proteasome is the proteolytically active component of the 26S proteasome complex. The encoded protein is degraded before the maturation of the 20S proteasome is complete. A variant in the 5' UTR of this gene has been associated with KLICK syndrome, a rare skin disorder.

Gene Name: proteasome maturation protein

Alternative Symbols: UMP1, PRAAS2, HSPC014, C13orf12, PNAS-110

Protein Name: Proteasome maturation protein

Molecular Weight: 15kDa

Gene ID: 51371

NCBI Accession: NP_057016

UniProt: Q9Y244