NCBP2 antibody (C-Term)

Catalog No. ABIN5515700

The Rabbit Polyclonal anti-NCBP2 antibody (ABIN5515700) specifically detects NCBP2 in WB. The antibody is reactive with Human samples.

Quick Overview for NCBP2 antibody (C-Term) (ABIN5515700)

Target: NCBP2 (Nuclear Cap Binding Protein Subunit 2 (NCBP2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NCBP2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NCBP2 Antibody

Binding Specificity: C-Term

Sequence: RYINGTRLDD RIIRTDWDAG FKEGRQYGRG RSGGQVRDEY RQDYDAGRGG

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human NCBP2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NCBP2

Target: NCBP2 (Nuclear Cap Binding Protein Subunit 2 (NCBP2))

Alternative Name: NCBP2

Background: The product of this gene is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. The encoded protein has an RNP domain commonly found in RNA binding proteins, and contains the cap-binding activity. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay. Multiple transcript variants encoding different isoforms have been found for this gene.

Alias Symbols: CBC2, NIP1, CBP20, PIG55

Protein Size: 156

Gene ID: 22916

NCBI Accession: NM_001042540, NP_001036005

UniProt: P52298

Pathways: Ribonucleoprotein Complex Subunit Organization, Methionine Biosynthetic Process