NCBP2 antibody (C-Term)

Catalog No. ABIN5515700

The Rabbit Polyclonal anti-NCBP2 antibody (ABIN5515700) specifically detects NCBP2 in WB. The antibody is reactive with Human samples.

Quick Overview for NCBP2 antibody (C-Term) (ABIN5515700)

Target: NCBP2 (Nuclear Cap Binding Protein Subunit 2 (NCBP2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NCBP2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NCBP2 Antibody

Binding Specificity: C-Term

Purpose: NCBP2 Antibody - C-terminal region

Sequence: RYINGTRLDD RIIRTDWDAG FKEGRQYGRG RSGGQVRDEY RQDYDAGRGG

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human NCBP2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP79922-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for NCBP2

Target: NCBP2 (Nuclear Cap Binding Protein Subunit 2 (NCBP2))

Alternative Name: NCBP2

Background:

Background Information: The product of this gene is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. The encoded protein has an RNP domain commonly found in RNA binding proteins, and contains the cap-binding activity. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Name: nuclear cap binding protein subunit 2

Alternative Symbols: CBC2, NIP1, CBP20, PIG55

Protein Name: nuclear cap-binding protein subunit 2

Molecular Weight: 17 kDa

Gene ID: 22916

NCBI Accession: NP_001036005

UniProt: P52298

Pathways: Ribonucleoprotein Complex Subunit Organization, Methionine Biosynthetic Process