PTS antibody (N-Term)

Catalog No. ABIN5515752

This Rabbit Polyclonal antibody specifically detects PTS in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Guinea Pig and Zebrafish (Danio rerio).

Quick Overview for PTS antibody (N-Term) (ABIN5515752)

Target: PTS (6-Pyruvoyltetrahydropterin Synthase (PTS))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTS antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PTS Antibody

Binding Specificity: N-Term

Purpose: PTS Antibody - N-terminal region

Sequence: SKFLSDEENL KLFGKCNNPN GHGHNYKVVV TVHGEIDPAT GMVMNLADLK

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against PTPS. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human PTPS

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP56099-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for PTS

Target: PTS (6-Pyruvoyltetrahydropterin Synthase (PTS))

Alternative Name: PTS

Background:

Background Information: The enzyme encoded by this gene catalyzes the elimination of inorganic triphosphate from dihydroneopterin triphosphate, which is the second and irreversible step in the biosynthesis of tetrahydrobiopterin from GTP. Tetrahydrobiopterin, also known as BH(4), is an essential cofactor and regulator of various enzyme activities, including enzymes involved in serotonin biosynthesis and NO synthase activity. Mutations in this gene result in hyperphenylalaninemia.

Gene Name: 6-pyruvoyltetrahydropterin synthase

Alternative Symbols: PTPS

Protein Name: 6-pyruvoyl tetrahydrobiopterin synthase

Molecular Weight: 15kDa

Gene ID: 5805

NCBI Accession: NP_000308

UniProt: Q03393