ALDOB antibody (N-Term)

Catalog No. ABIN5515769

The Rabbit Polyclonal anti-ALDOB antibody (ABIN5515769) specifically detects ALDOB in WB and IHC. The antibody is reactive with Human, Mouse, Rat, Rabbit, Guinea Pig, Horse, Cow, Dog, Sheep, Saccharomyces cerevisiae and Zebrafish (Danio rerio) samples.

Quick Overview for ALDOB antibody (N-Term) (ABIN5515769)

Target: ALDOB (Aldolase B, Fructose-Bisphosphate (ALDOB))

Reactivity: Human, Mouse, Rat, Rabbit, Guinea Pig, Horse, Cow, Dog, Sheep, Saccharomyces cerevisiae, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALDOB antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-ALDOB Antibody

Binding Specificity: N-Term

Purpose: ALDOB Antibody - N-terminal region

Sequence: ADESVGTMGN RLQRIKVENT EENRRQFREI LFSVDSSINQ SIGGVILFHE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Yeast: 90%, Zebrafish: 75%

Characteristics: This is a rabbit polyclonal antibody against ALDOB. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human ALDOB

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP41364-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for ALDOB

Target: ALDOB (Aldolase B, Fructose-Bisphosphate (ALDOB))

Alternative Name: ALDOB

Background:

Background Information: Fructose-1,6-bisphosphate aldolase (EC 4.1.2.13) is a tetrameric glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Vertebrates have 3 aldolase isozymes which are distinguished by their electrophoretic and catalytic properties. Differences indicate that aldolases A, B, and C are distinct proteins, the products of a family of related 'housekeeping' genes exhibiting developmentally regulated expression of the different isozymes. The developing embryo produces aldolase A, which is produced in even greater amounts in adult muscle where it can be as much as 5 % of total cellular protein. In adult liver, kidney and intestine, aldolase A expression is repressed and aldolase B is produced. In brain and other nervous tissue, aldolase A and C are expressed about equally. There is a high degree of homology between aldolase A and C. Defects in ALDOB cause hereditary fructose intolerance.

Gene Name: aldolase B, fructose-bisphosphate

Alternative Symbols: ALDB, ALDO2

Protein Name: Fructose-bisphosphate aldolase B

Molecular Weight: 40kDa

Gene ID: 229

NCBI Accession: NP_000026

UniProt: P05062