CCR9 antibody (N-Term)

Catalog No. ABIN5515835

The Rabbit Polyclonal anti-CCR9 antibody (ABIN5515835) specifically detects CCR9 in WB. The antibody is reactive with Human samples.

Quick Overview for CCR9 antibody (N-Term) (ABIN5515835)

Target: CCR9 (Chemokine (C-C Motif) Receptor 9 (CCR9))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCR9 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CCR9 Antibody

Binding Specificity: N-Term

Purpose: CCR9 Antibody - N-terminal region

Sequence: PTDFTSPIPN MADDYGSEST SSMEDYVNFN FTDFYCEKNN VRQFASHFLP

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CCR9

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP79684-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for CCR9

Target: CCR9 (Chemokine (C-C Motif) Receptor 9 (CCR9))

Alternative Name: CCR9

Background:

Background Information: The protein encoded by this gene is a member of the beta chemokine receptor family. It is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are key regulators of the thymocytes migration and maturation in normal and inflammation conditions. The specific ligand of this receptor is CCL25. It has been found that this gene is differentially expressed by T lymphocytes of small intestine and colon, suggested a role in the thymocytes recruitment and development that may permit functional specialization of immune responses in different segment of the gastrointestinal tract. This gene is mapped to the chemokine receptor gene cluster region. Two alternatively spliced transcript variants have been described. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Name: C-C motif chemokine receptor 9

Alternative Symbols: GPR28, CDw199, GPR-9-6, CC-CKR-9

Protein Name: C-C chemokine receptor type 9

Molecular Weight: 41 kDa

Gene ID: 10803

NCBI Accession: NP_001243298

UniProt: P51686