CPOX antibody (C-Term)

Catalog No. ABIN5515941

This Rabbit Polyclonal antibody specifically detects CPOX in WB. It exhibits reactivity toward Human.

Quick Overview for CPOX antibody (C-Term) (ABIN5515941)

Target: CPOX (Coproporphyrinogen Oxidase (CPOX))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CPOX antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CPOX Antibody

Binding Specificity: C-Term

Sequence: EVFRFVQSCA RAVVPSYIPL VKKHCDDSFT PQEKLWQQLR RGRYVEFNLL

Characteristics: This is a rabbit polyclonal antibody against CPOX. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human CPOX

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CPOX

Target: CPOX (Coproporphyrinogen Oxidase (CPOX))

Alternative Name: CPOX

Background: The protein encoded by this gene is the sixth enzyme of the heme biosynthetic pathway. The encoded enzyme is soluble and found in the intermembrane space of mitochondria. This enzyme catalyzes the stepwise oxidative decarboxylation of coproporphyrinogen III to protoporphyrinogen IX, a precursor of heme. Defects in this gene are a cause of hereditary coproporphyria (HCP).

Alias Symbols: CPOX, CPO, CPX,

Protein Interaction Partner: SUMO1, UBC, UBE2G2, AIFM1, FH, CUL3, ELAVL1,

Protein Size: 454

Gene ID: 1371

NCBI Accession: NP_000088

UniProt: P36551