CPOX antibody (AA 111-454)

Catalog No. ABIN5776081

The Mouse Monoclonal anti-CPOX antibody is suitable to detect CPOX in samples from Human. It has been validated for WB, ELISA, IF and ICC.

Quick Overview for CPOX antibody (AA 111-454) (ABIN5776081)

Target: CPOX (Coproporphyrinogen Oxidase (CPOX))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CPOX antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: AT36B10

Product Details anti-CPOX Antibody

Binding Specificity: AA 111-454

Purpose: Human CPOX antibody

Purification: Purified

Immunogen: Recombinant human CPOX (111-454aa) purified from E. coli

Isotype: IgG1 kappa

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing cycles

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Target Details for CPOX

Target: CPOX (Coproporphyrinogen Oxidase (CPOX))

Alternative Name: CPOX

Background: Coproporphyrinogen-III oxidase, mitochondrial precursor, also known as CPOX, is a 454 amino acid mitochondrial enzyme that is localized to the inner membrane space of erythrocytes. It participates in the sixth step of heme biosynthesis by catalyzing the formation of protoporphyrinogen IX from coproporphyrinogen III. Mutations in human CPOX gene predict the clinical outcome of the disease, with either hepatic hereditary coproporphyria or hematological manifestations of erythropoietic harderoporphyria.

NCBI Accession: NP_000088