Keratin 72 antibody (C-Term)

Catalog No. ABIN5515950

This Rabbit Polyclonal antibody specifically detects Keratin 72 in WB. It exhibits reactivity toward Human, Cow, Horse and Rat.

Quick Overview for Keratin 72 antibody (C-Term) (ABIN5515950)

Target: Keratin 72 (KRT72)

Reactivity: Human, Cow, Horse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Keratin 72 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Keratin 72 Antibody

Binding Specificity: C-Term

Purpose: KRT72 Antibody - C-terminal region

Sequence: GFSMGFGASS SYSYKTAAAD VKTKGSCGSE LKDPLAKTSG SSCATKKASR

Predicted Reactivity: Cow: 100%, Horse: 93%, Human: 100%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against KRT72. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human KRT72

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP70731-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Keratin 72

Target: Keratin 72 (KRT72)

Alternative Name: KRT72

Background:

Background Information: Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells. The type II keratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This gene encodes a type II keratin that is specifically expressed in the inner root sheath of hair follicles. The type II keratins are clustered in a region of chromosome 12q12-q13. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative Symbols: K72, KRT6, CK-72, K6irs, K6IRS2, KRT6IRS2

Molecular Weight: 56kDa

Gene ID: 140807

NCBI Accession: NP_542785

UniProt: Q14CN4