OSBPL2 antibody (N-Term)

Catalog No. ABIN5516124

This Rabbit Polyclonal antibody specifically detects OSBPL2 in WB. It exhibits reactivity toward Human.

Quick Overview for OSBPL2 antibody (N-Term) (ABIN5516124)

Target: OSBPL2 (Oxysterol Binding Protein-Like 2 (OSBPL2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OSBPL2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-OSBPL2 Antibody

Binding Specificity: N-Term

Purpose: OSBPL2 Antibody - N-terminal region

Sequence: DSDNSSGEFS EANQKVTGMI DLDTSKNNRI GKTGERPSQE NGIQKHRTSL

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human OSBPL2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP78593-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for OSBPL2

Target: OSBPL2 (Oxysterol Binding Protein-Like 2 (OSBPL2))

Alternative Name: OSBPL2

Background:

Background Information: This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although the encoded protein contains only the sterol-binding domain. In vitro studies have shown that the encoded protein can bind strongly to phosphatic acid and weakly to phosphatidylinositol 3-phosphate, but cannot bind to 25-hydroxycholesterol. The protein associates with the Golgi apparatus. Transcript variants encoding different isoforms have been described.

Gene Name: oxysterol binding protein like 2

Alternative Symbols: ORP2, ORP-2, DFNA67, DNFA67

Protein Name: oxysterol-binding protein-related protein 2

Molecular Weight: 52 kDa

Gene ID: 9885

NCBI Accession: NP_055650

UniProt: Q9H1P3