Adracalin antibody (N-Term)

Catalog No. ABIN5516315

The Rabbit Polyclonal anti-Adracalin antibody (ABIN5516315) specifically detects Adracalin in WB. The antibody is reactive with Human samples.

Quick Overview for Adracalin antibody (N-Term) (ABIN5516315)

Target: Adracalin (AAAS) (Achalasia, Adrenocortical Insufficiency, Alacrimia (AAAS))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Adracalin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Adracalin Antibody

Binding Specificity: N-Term

Purpose: AAAS Antibody - N-terminal region

Sequence: EHNNELVTGS SYESPPPDFR GQWINLPVLQ LTKDPLKTPG RLDHGTRTAF

Characteristics: This is a rabbit polyclonal antibody against AAAS. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human AAAS

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP72542-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Adracalin

Target: Adracalin (AAAS) (Achalasia, Adrenocortical Insufficiency, Alacrimia (AAAS))

Alternative Name: AAAS

Background:

Background Information: The protein encoded by this gene is a member of the WD-repeat family of regulatory proteins and may be involved in normal development of the peripheral and central nervous system. The encoded protein is part of the nuclear pore complex and is anchored there by NDC1. Defects in this gene are a cause of achalasia-addisonianism-alacrima syndrome (AAAS), also called triple-A syndrome or Allgrove syndrome. Two transcript variants encoding different isoforms have been found for this gene.

Alternative Symbols: AAA, AAASb, GL003, ALADIN, ADRACALA, ADRACALIN

Molecular Weight: 60kDa

Gene ID: 8086

NCBI Accession: NP_056480

UniProt: Q9NRG9