C1GALT1C1 antibody (N-Term)

Catalog No. ABIN5516325

This Rabbit Polyclonal antibody specifically detects C1GALT1C1 in WB. It exhibits reactivity toward Human.

Quick Overview for C1GALT1C1 antibody (N-Term) (ABIN5516325)

Target: C1GALT1C1 (C1GALT1-Specific Chaperone 1 (C1GALT1C1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C1GALT1C1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-C1GALT1C1 Antibody

Binding Specificity: N-Term

Sequence: GNRMHHHEHH HLQAPNKEDI LKISEDERME LSKSFRVYCI ILVKPKDVSL

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human C1GALT1C1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for C1GALT1C1

Target: C1GALT1C1 (C1GALT1-Specific Chaperone 1 (C1GALT1C1))

Alternative Name: C1GALT1C1

Background: This gene encodes a type II transmembrane protein that is similar to the core 1 beta1,3-galactosyltransferase 1, which catalyzes the synthesis of the core-1 structure, also known as Thomsen-Friedenreich antigen, on O-linked glycans. This gene product lacks the galactosyltransferase activity itself, but instead acts as a molecular chaperone required for the folding, stability and full activity of the core 1 beta1,3-galactosyltransferase 1. Mutations in this gene have been associated with Tn syndrome. Alternatively spliced transcript variants encoding the same protein have been identified.

Alias Symbols: TNPS, COSMC, MST143, C1GALT2, HSPC067, C38H2-L1

Protein Size: 375

Gene ID: 29071

NCBI Accession: NM_001011551, NP_001011551

UniProt: Q96EU7