HERV-FRD Provirus Ancestral Env Polyprotein (Herv-frd) (C-Term) antibody
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- Target See all HERV-FRD Provirus Ancestral Env Polyprotein (Herv-frd) Antibodies
- HERV-FRD Provirus Ancestral Env Polyprotein (Herv-frd)
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Binding Specificity
- C-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- Un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- PLVSLLLLLL FGPCLLNLIT QFVSSRLQAI KLQTNLSAGR HPRNIQESPF
- Predicted Reactivity
- Human: 100%
- Characteristics
- This is a rabbit polyclonal antibody against ERVFRD-1. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human ERVFRD-1
- Top Product
- Discover our top product Herv-frd Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- HERV-FRD Provirus Ancestral Env Polyprotein (Herv-frd)
- Alternative Name
- ERVFRD-1 (Herv-frd Products)
- Synonyms
- ERVFRDE1 antibody, GLLL6191 antibody, HERV-FRD antibody, HERV-W/FRD antibody, UNQ6191 antibody, envFRD antibody, Gm52 antibody, Syna antibody, endogenous retrovirus group FRD member 1, envelope antibody, ERVFRD-1 antibody, Ervfrd-1 antibody
- Target Type
- Viral Protein
- Background
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Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels, suggesting that HERVs are functionally important in reproduction. This gene is part of a human endogenous retrovirus provirus on chromosome 6 that has inactivating mutations in the gag and pol genes. This gene is the envelope glycoprotein gene which appears to have been selectively preserved. The gene's protein product plays a major role in placental development and trophoblast fusion. The protein has the characteristics of a typical retroviral envelope protein, including a cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer.
Alias Symbols: ERVFRD-1, ERVFRDE1, UNQ6191/PRO20218,
Protein Interaction Partner: APP,
Protein Size: 538 - Gene ID
- 405754
- NCBI Accession
- NP_997465
- UniProt
- P60508
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