FBXO46 antibody (C-Term)

Catalog No. ABIN5516516

Product Details anti-FBXO46 Antibody

Target: FBXO46 (F-Box Protein 46 (FBXO46))

Binding Specificity: C-Term

Reactivity: Human, Dog, Guinea Pig, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBXO46 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: VDVVVTGVVD ECIFFGKDGT KNVKEETVCL TVSPEEPPPP GQLFFLQNRG

Predicted Reactivity: Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against FBXO46. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human FBXO46

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FBXO46

Target: FBXO46 (F-Box Protein 46 (FBXO46))

Alternative Name: FBXO46 (FBXO46 Products)

Synonyms: FBXO46 antibody, 20D7-FC4 antibody, FBXO34L antibody, Fbx46 antibody, 4932704E22Rik antibody, Fbxo34l antibody, F-box protein 46 antibody, F-box protein 46 L homeolog antibody, FBXO46 antibody, fbxo46.L antibody, fbxo46 antibody, Fbxo46 antibody

Background: Members of the F-box protein family, such as FBXO46, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1, cullin, and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains.

Alias Symbols: 20D7-FC4, FBXO34L, Fbx46

Protein Interaction Partner: CUL1, HNRNPR, RUVBL1, SLC25A11, TCP1, SKP1, MCM4, DHX9, DDX5, NEDD8, COPS5,

Protein Size: 603

Gene ID: 23403

NCBI Accession: NM_001080469, NP_001073938

UniProt: Q6PJ61