C1QC antibody (Middle Region)

Catalog No. ABIN5516555

The Rabbit Polyclonal anti-C1QC antibody (ABIN5516555) specifically detects C1QC in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Dog, Horse, Pig and Rabbit samples.

Quick Overview for C1QC antibody (Middle Region) (ABIN5516555)

Target: C1QC (Complement Component 1, Q Subcomponent, C Chain (C1QC))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C1QC antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-C1QC Antibody

Binding Specificity: Middle Region

Sequence: GKNGPMGPPG MPGVPGPMGI PGEPGEEGRY KQKFQSVFTV TRQTHQPPAP

Predicted Reactivity: Cow: 92%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Pig: 100%, Rabbit: 92%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against C1QC. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human C1QC

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for C1QC

Target: C1QC (Complement Component 1, Q Subcomponent, C Chain (C1QC))

Alternative Name: C1QC

Background: This gene encodes a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. A deficiency in C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N-terminus, and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. This gene encodes the C-chain polypeptide of human complement subcomponent C1q. Alternatively spliced transcript variants that encode the same protein have been found for this gene.

Alias Symbols: C1QG

Protein Interaction Partner: FN1, APOA1, PTX3, FKBP2, C1QB, C1QA,

Protein Size: 245

Gene ID: 714

NCBI Accession: NP_758957

UniProt: P02747

Pathways: Complement System