APBA2 antibody (N-Term)

Catalog No. ABIN5516584

The Rabbit Polyclonal anti-APBA2 antibody is suitable to detect APBA2 in samples from Human. It has been validated for WB.

Quick Overview for APBA2 antibody (N-Term) (ABIN5516584)

Target: APBA2 (Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 2 (APBA2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APBA2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-APBA2 Antibody

Binding Specificity: N-Term

Sequence: PAPEEQECHN HSPDGDSSSD YVNNTSEEED YDEGLPEEEE GITYYIRYCP

Characteristics: This is a rabbit polyclonal antibody against APBA2. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human APBA2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for APBA2

Target: APBA2 (Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 2 (APBA2))

Alternative Name: APBA2

Background: The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. Multiple transcript variants encoding different isoforms have been found for this gene.

Alias Symbols: APBA2, MINT2, X11L,

Protein Size: 749

Gene ID: 321

UniProt: Q99767

Pathways: Synaptic Vesicle Exocytosis