MRPL23 antibody (C-Term)

Catalog No. ABIN5516623

The Rabbit Polyclonal anti-MRPL23 antibody is suitable to detect MRPL23 in samples from Human. It has been validated for WB.

Quick Overview for MRPL23 antibody (C-Term) (ABIN5516623)

Target: MRPL23 (Mitochondrial Ribosomal Protein L23 (MRPL23))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MRPL23 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MRPL23 Antibody

Binding Specificity: C-Term

Purpose: MRPL23 Antibody - C-terminal region

Sequence: HGQTFTFPDL FPEKDESPEG SAADDLYSML EEERQQRQSS DPRRGGVPSW

Characteristics: This is a rabbit polyclonal antibody against RM23. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen for Anti-MRPL23 antibody is: synthetic peptide directed towards the C-terminal region of Human RM23

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP74071-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for MRPL23

Target: MRPL23 (Mitochondrial Ribosomal Protein L23 (MRPL23))

Alternative Name: MRPL23

Background:

Background Information: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. The gene is biallelically expressed, despite its location within a region of imprinted genes on chromosome 11.

Gene Name: mitochondrial ribosomal protein L23

Alternative Symbols: RPL23, L23MRP, RPL23L

Molecular Weight: 16 kDa

Gene ID: 6150

NCBI Accession: NP_066957

UniProt: Q16540