FASTK antibody (N-Term)

Catalog No. ABIN5516730

This Rabbit Polyclonal antibody specifically detects FASTK in WB. It exhibits reactivity toward Human.

Quick Overview for FASTK antibody (N-Term) (ABIN5516730)

Target: FASTK (Fas-Activated serine/threonine Kinase (FASTK))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FASTK antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FASTK Antibody

Binding Specificity: N-Term

Purpose: FASTK Antibody - N-terminal region

Sequence: MRRPRGEPGP RAPRPTEGAT CAGPGESWSP SPNSMLRVLL SAQTSPARLS

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N region of human FASTK

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP77054-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for FASTK

Target: FASTK (Fas-Activated serine/threonine Kinase (FASTK))

Alternative Name: FASTK

Background:

Background Information: The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis-promoting nuclear RNA-binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full-length natures have not yet been determined.

Gene Name: Fas activated serine/threonine kinase

Alternative Symbols: FAST

Protein Name: fas-activated serine/threonine kinase

Molecular Weight: 60 kDa

Gene ID: 10922

NCBI Accession: NP_001245390

UniProt: Q14296