KIRREL3 antibody (C-Term)

Catalog No. ABIN5516813

The Rabbit Polyclonal anti-KIRREL3 antibody (ABIN5516813) specifically detects KIRREL3 in WB. The antibody is reactive with Human samples.

Quick Overview for KIRREL3 antibody (C-Term) (ABIN5516813)

Target: KIRREL3 (Kin of IRRE Like 3 (KIRREL3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KIRREL3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-KIRREL3 Antibody

Binding Specificity: C-Term

Purpose: KIRREL3 Antibody - C-terminal region

Sequence: TQCDSSVSSS GKQDGYVQFD KASKASASSS HHSQSSSQNS DPSRPLQRRM

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human KIRREL3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP78495-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for KIRREL3

Target: KIRREL3 (Kin of IRRE Like 3 (KIRREL3))

Alternative Name: KIRREL3

Background:

Background Information: The protein encoded by this gene is a member of the nephrin-like protein family. These proteins are expressed in fetal and adult brain, and also in podocytes of kidney glomeruli. The cytoplasmic domains of these proteins interact with the C-terminus of podocin, also expressed in the podocytes, cells involved in ensuring size- and charge-selective ultrafiltration. Mutations in this gene are associated with mental retardation autosomal dominant type 4 (MRD4). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Name: kin of IRRE like 3 (Drosophila)

Alternative Symbols: MRD4, KIRRE, NEPH2, PRO4502

Protein Name: kin of IRRE-like protein 3

Molecular Weight: 85 kDa

Gene ID: 84623

NCBI Accession: NP_001155179

UniProt: Q8IZU9