DPH5 antibody (Middle Region)

Catalog No. ABIN5517030

This Rabbit Polyclonal antibody specifically detects DPH5 in WB. It exhibits reactivity toward Human.

Quick Overview for DPH5 antibody (Middle Region) (ABIN5517030)

Target: DPH5 (DPH5 Homolog (DPH5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DPH5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DPH5 Antibody

Binding Specificity: Middle Region

Sequence: QLYKFGETVS IVFWTDTWRP ESFFDKVKKN RQNGMHTLCL LDIKVKEQSL

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human DPH5

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DPH5

Target: DPH5 (DPH5 Homolog (DPH5))

Alternative Name: DPH5

Background: This gene encodes a component of the diphthamide synthesis pathway. Diphthamide is a post-translationally modified histidine residue found only on translation elongation factor 2. It is conserved from archaebacteria to humans, and is targeted by diphtheria toxin and Pseudomonas exotoxin A to halt cellular protein synthesis. The yeast and Chinese hamster homologs of this protein catalyze the trimethylation of the histidine residue on elongation factor 2, resulting in a diphthine moiety that is subsequently amidated to yield diphthamide. Multiple transcript variants encoding different isoforms have been found for this gene.

Alias Symbols: AD-018, CGI-30, NPD015, HSPC143

Protein Size: 234

Gene ID: 51611

NCBI Accession: NM_001077394, NP_001070862

Pathways: SARS-CoV-2 Protein Interactome