NAGLU antibody (C-Term)

Catalog No. ABIN5517086

This anti-NAGLU antibody is a Rabbit Polyclonal antibody detecting NAGLU in WB. Suitable for Human.

Quick Overview for NAGLU antibody (C-Term) (ABIN5517086)

Target: NAGLU (N-Acetylglucosaminidase, alpha (NAGLU))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NAGLU antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NAGLU Antibody

Binding Specificity: C-Term

Sequence: LEALVDSVAQ GIPFQQHQFD KNVFQLEQAF VLSKQRYPSQ PRGDTVDLAK

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human NAGLU

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NAGLU

Target: NAGLU (N-Acetylglucosaminidase, alpha (NAGLU))

Alternative Name: NAGLU

Background: This gene encodes an enzyme that degrades heparan sulfate by hydrolysis of terminal N-acetyl-D-glucosamine residues in N-acetyl-alpha-D-glucosaminides. Defects in this gene are the cause of mucopolysaccharidosis type IIIB (MPS-IIIB), also known as Sanfilippo syndrome B. This disease is characterized by the lysosomal accumulation and urinary excretion of heparan sulfate.

Alias Symbols: NAG, MPS3B, UFHSD, MPS-IIIB

Protein Size: 639

Gene ID: 4669

NCBI Accession: NM_000263, NP_000254

UniProt: P54802

Pathways: Glycosaminoglycan Metabolic Process