PAR1 antibody (C-Term)

Catalog No. ABIN5517088

The Rabbit Polyclonal anti-PAR1 antibody has been validated for WB. It is suitable to detect PAR1 in samples from Human, Mouse, Rat, Pig, Guinea Pig, Dog, Horse and Cow.

Quick Overview for PAR1 antibody (C-Term) (ABIN5517088)

Target: PAR1 (F2R) (Coagulation Factor II (thrombin) Receptor (F2R))

Reactivity: Human, Mouse, Rat, Pig, Guinea Pig, Dog, Horse, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAR1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PAR1 Antibody

Binding Specificity: C-Term

Sequence: ASSECQRYVY SILCCKESSD PSSYNSSGQL MASKMDTCSS NLNNSIYKKL

Predicted Reactivity: Cow: 79%, Dog: 100%, Guinea Pig: 79%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against PAR1. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human PAR1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PAR1

Target: PAR1 (F2R) (Coagulation Factor II (thrombin) Receptor (F2R))

Alternative Name: PAR1

Background: Coagulation factor II receptor is a 7-transmembrane receptor involved in the regulation of thrombotic response. Proteolytic cleavage leads to the activation of the receptor. F2R is a G-protein coupled receptor family member.

Alias Symbols: F2R, CF2R, PAR1, TR,

Protein Size: 425

Gene ID: 2149

NCBI Accession: NP_001983

UniProt: P25116

Pathways: Nuclear Receptor Transcription Pathway, Skeletal Muscle Fiber Development, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus