CSTA antibody (N-Term)

Catalog No. ABIN5517108

This Rabbit Polyclonal antibody specifically detects CSTA in WB. It exhibits reactivity toward Human.

Quick Overview for CSTA antibody (N-Term) (ABIN5517108)

Target: CSTA (Cystatin A (Stefin A) (CSTA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CSTA antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CSTA Antibody

Binding Specificity: N-Term

Purpose: CSTA Antibody - N-terminal region

Sequence: GGLSEAKPAT PEIQEIVDKV KPQLEEKTNE TYGKLEAVQY KTQVVAGTNY

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CSTA

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP78214-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for CSTA

Target: CSTA (Cystatin A (Stefin A) (CSTA))

Alternative Name: CSTA

Background:

Background Information: The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins, and kininogens. This gene encodes a stefin that functions as a cysteine protease inhibitor, forming tight complexes with papain and the cathepsins B, H, and L. The protein is one of the precursor proteins of cornified cell envelope in keratinocytes and plays a role in epidermal development and maintenance. Stefins have been proposed as prognostic and diagnostic tools for cancer.

Gene Name: cystatin A (stefin A)

Alternative Symbols: AREI, PSS4, STF1, STFA

Protein Name: cystatin-A

Molecular Weight: 11 kDa

Gene ID: 1475

NCBI Accession: NP_005204

UniProt: P01040

Pathways: Response to Water Deprivation