MATK antibody (C-Term)

Catalog No. ABIN5517155

The Rabbit Polyclonal anti-MATK antibody (ABIN5517155) specifically detects MATK in WB. The antibody is reactive with Human samples.

Quick Overview for MATK antibody (C-Term) (ABIN5517155)

Target: MATK (Megakaryocyte-Associated tyrosine Kinase (MATK))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MATK antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MATK Antibody

Binding Specificity: C-Term

Sequence: SSCWEAEPAR RPPFRKLAEK LARELRSAGA PASVSGQDAD GSTSPRSQEP

Characteristics: This is a rabbit polyclonal antibody against MATK. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human MATK

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MATK

Target: MATK (Megakaryocyte-Associated tyrosine Kinase (MATK))

Alternative Name: MATK

Background: The protein encoded by this gene has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer. Three alternatively spliced transcript variants that encode different isoforms have been described for this gene.

Alias Symbols: MATK, CTK, HYL,

Protein Interaction Partner: BRCA1, UBC, HSP90AA1, ERBB2, MYC, CACNA1A, PXN, PTK2B, NTRK1, SRC, CD36, LYN, KIT, EWSR1,

Protein Size: 507

Gene ID: 4145

NCBI Accession: NP_647612

UniProt: P42679