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MATK antibody (C-Term)
MATK
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-MATK Antibody
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Target
See all MATK Antibodies
MATK
(Megakaryocyte-Associated tyrosine Kinase (MATK))
Binding Specificity
All epitopes for MATK antibodies
C-Term
Reactivity
All reactivities for MATK antibodies
Human
Host
All hosts for MATK antibodies
Rabbit
Clonality
All clonalities for MATK antibodies
Polyclonal
Conjugate
All conjugates for MATK antibodies
This MATK antibody is un-conjugated
Application
All applications for MATK antibodies
Western Blotting (WB)
Sequence
SSCWEAEPAR RPPFRKLAEK LARELRSAGA PASVSGQDAD GSTSPRSQEP
Characteristics
This is a rabbit polyclonal antibody against MATK. It was validated on Western Blot.
Purification
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of Human MATK
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for MATK
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Target
MATK
(Megakaryocyte-Associated tyrosine Kinase (MATK))
Alternative Name
MATK (MATK Products )
Synonyms
si:ch211-63j24.2 antibody, CHK antibody, CTK antibody, HHYLTK antibody, HYL antibody, HYLTK antibody, Lsk antibody, Ntk antibody, Batk antibody, megakaryocyte-associated tyrosine kinase antibody, zinc finger RNA binding protein 2 antibody, matk antibody, MATK antibody, Matk antibody, ZFR2 antibody
Background
The protein encoded by this gene has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer. Three alternatively spliced transcript variants that encode different isoforms have been described for this gene. Alias Symbols: MATK, CTK, HYL, Protein Interaction Partner: BRCA1, UBC, HSP90AA1, ERBB2, MYC, CACNA1A, PXN, PTK2B, NTRK1, SRC, CD36, LYN, KIT, EWSR1, Protein Size: 507
Gene ID
4145
NCBI Accession
NP_647612
UniProt
P42679
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