MBL2 antibody (N-Term)

Catalog No. ABIN5517156

This Rabbit Polyclonal antibody specifically detects MBL2 in WB. It exhibits reactivity toward Human, Rat, Mouse, Cow, Goat, Sheep, Guinea Pig, Rabbit and Zebrafish (Danio rerio).

Quick Overview for MBL2 antibody (N-Term) (ABIN5517156)

Target: MBL2 (Mannose-Binding Lectin (Protein C) 2, Soluble (MBL2))

Reactivity: Human, Rat, Mouse, Cow, Goat, Sheep, Guinea Pig, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MBL2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MBL2 Antibody

Binding Specificity: N-Term

Sequence: SETVTCEDAQ KTCPAVIACS SPGINGFPGK DGRDGTKGEK GEPGQGLRGL

Predicted Reactivity: Cow: 92%, Goat: 100%, Guinea Pig: 92%, Human: 100%, Mouse: 93%, Rabbit: 92%, Rat: 92%, Sheep: 91%, Zebrafish: 83%

Characteristics: This is a rabbit polyclonal antibody against MBL2. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human MBL2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MBL2

Target: MBL2 (Mannose-Binding Lectin (Protein C) 2, Soluble (MBL2))

Alternative Name: MBL2

Background: This gene encodes the soluble mannose-binding lectin or mannose-binding protein found in serum. The protein encoded belongs to the collectin family and is an important element in the innate immune system. The protein recognizes mannose and N-acetylglucosamine on many microorganisms, and is capable of activating the classical complement pathway. Deficiencies of this gene have been associated with susceptibility to autoimmune and infectious diseases.

Alias Symbols: MBL2, COLEC1, MBL,

Protein Interaction Partner: MASP2, MAD2L1, MASP1, MBL2, PTPRC, KRT1, CD93, CALCR, CALR,

Protein Size: 248

Gene ID: 4153

NCBI Accession: XP_006717924

UniProt: P11226

Pathways: Complement System, Positive Regulation of Immune Effector Process