NRL antibody (C-Term)

Catalog No. ABIN5517221

The Rabbit Polyclonal anti-NRL antibody (ABIN5517221) specifically detects NRL in WB. The antibody is reactive with Human, Rat, Guinea Pig, Horse, Dog and Rabbit samples.

Quick Overview for NRL antibody (C-Term) (ABIN5517221)

Target: NRL (Neural Retina Leucine Zipper (NRL))

Reactivity: Human, Rat, Guinea Pig, Horse, Dog, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NRL antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-NRL Antibody

Binding Specificity: C-Term

Purpose: NRL Antibody - C-terminal region

Sequence: LEAERARLAA QLDALRAEVA RLARERDLYK ARCDRLTSSG PGSGDPSHLF

Predicted Reactivity: Dog: 92%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against NRL. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human NRL

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP58167-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for NRL

Target: NRL (Neural Retina Leucine Zipper (NRL))

Alternative Name: NRL

Background:

Background Information: This gene encodes a basic motif-leucine zipper transcription factor of the Maf subfamily. The encoded protein is conserved among vertebrates and is a critical intrinsic regulator of photoceptor development and function. Mutations in this gene have been associated with retinitis pigmentosa and retinal degenerative diseases.

Gene Name: neural retina leucine zipper

Alternative Symbols: RP27, D14S46E, NRL-MAF

Protein Name: Neural retina-specific leucine zipper protein

Molecular Weight: 26kDa

Gene ID: 4901

NCBI Accession: XP_005267767

UniProt: P54845