PDE6D antibody (N-Term)

Catalog No. ABIN5517276

This Rabbit Polyclonal antibody specifically detects PDE6D in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit and Zebrafish (Danio rerio).

Quick Overview for PDE6D antibody (N-Term) (ABIN5517276)

Target: PDE6D (phosphodiesterase 6D, CGMP-Specific, Rod, delta (PDE6D))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDE6D antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PDE6D Antibody

Binding Specificity: N-Term

Sequence: NLRDAETGKI LWQGTEDLSV PGVEHEARVP KKILKCKAVS RELNFSSTEQ

Predicted Reactivity: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against PDE6D. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human PDE6D

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PDE6D

Target: PDE6D (phosphodiesterase 6D, CGMP-Specific, Rod, delta (PDE6D))

Alternative Name: PDE6D

Background: PDE6D acts as a GTP specific dissociation inhibitor (GDI). It increases the affinity of ARL3 for GTP by several orders of magnitude and does so by decreasing the nucleotide dissociation rate. It stabilizes ARL3-GTP by decreasing the nucleotide dissociation.

Alias Symbols: PDE6D, PDED,

Protein Interaction Partner: ARL16, ARL2, UBC, PTGIR, COPS5, CUL1, FAM219A, ARL15, RND1, GRK7, RAD23A, ARL3, CETN3, RAB13, RAB18, RHEB, RPGR, HRAS, GRK1, RAP2B, RAP1A, RHOA, RHOB, RAB8A, GNAI1, RASA1, CDC42,

Protein Size: 150

Gene ID: 5147

NCBI Accession: NP_002592

UniProt: O43924