PDE6D antibody (AA 1-150)

Catalog No. ABIN7269303

Product Details anti-PDE6D Antibody

Target: PDE6D (phosphodiesterase 6D, CGMP-Specific, Rod, delta (PDE6D))

Binding Specificity: AA 1-150

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDE6D antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Purpose: PDE6D Rabbit pAb

Sequence: MSAKDERARE ILRGFKLNWM NLRDAETGKI LWQGTEDLSV PGVEHEARVP KKILKCKAVS RELNFSSTEQ MEKFRLEQKV YFKGQCLEEW FFEFGFVIPN STNTWQSLIE AAPESQMMPA SVLTGNVIIE TKFFDDDLLV STSRVRLFYV

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human PDE6D (NP_002592.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PDE6D

Target: PDE6D (phosphodiesterase 6D, CGMP-Specific, Rod, delta (PDE6D))

Alternative Name: PDE6D (PDE6D Products)

Synonyms: zgc:92605 antibody, PDE6D antibody, PDED antibody, AI841218 antibody, PrBP/delta antibody, phosphodiesterase 6D antibody, phosphodiesterase 6D, cGMP-specific, rod, delta antibody, Pde6d antibody, PDE6D antibody, pde6d antibody

Background: This gene encodes the delta subunit of rod-specific photoreceptor phosphodiesterase (PDE), a key enzyme in the phototransduction cascade. A similar protein in cow functions in solubilizing membrane-bound PDE. In addition to its role in the PDE complex, the encoded protein is thought to bind to prenyl groups of proteins to target them to subcellular organelles called cilia. Mutations in this gene are associated with Joubert syndrome-22. Alternative splicing results in multiple splice variants.,PDE6D,JBTS22,PDED,Signal Transduction,PDE6D

Molecular Weight: 17kDa

Gene ID: 5147

UniProt: O43924