RAPSN antibody (C-Term)

Catalog No. ABIN5517286

The Rabbit Polyclonal anti-RAPSN antibody is suitable to detect RAPSN in samples from Human, Mouse, Rat, Dog, Cow, Guinea Pig, Rabbit, Zebrafish (Danio rerio) and Pig. It has been validated for WB.

Quick Overview for RAPSN antibody (C-Term) (ABIN5517286)

Target: RAPSN (Receptor-Associated Protein of The Synapse (RAPSN))

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Rabbit, Zebrafish (Danio rerio), Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAPSN antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RAPSN Antibody

Binding Specificity: C-Term

Purpose: RAPSN Antibody - C-terminal region

Sequence: ELYCGLCGES IGEKNSRLQA LPCSHIFHLR CLQNNGTRSC PNCRRSSMKP

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 79%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against RAPSN. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human RAPSN

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP43047-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for RAPSN

Target: RAPSN (Receptor-Associated Protein of The Synapse (RAPSN))

Alternative Name: RAPSN

Background:

Background Information: This gene encodes a member of a family of proteins that are receptor associated proteins of the synapse. The encoded protein contains a conserved cAMP-dependent protein kinase phosphorylation site, and plays a critical role in clustering and anchoring nicotinic acetylcholine receptors at synaptic sites by linking the receptors to the underlying postsynaptic cytoskeleton, possibly by direct association with actin or spectrin. Mutations in this gene may play a role in postsynaptic congenital myasthenic syndromes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene Name: receptor-associated protein of the synapse

Alternative Symbols: FADS, CMS11, CMS4C, FADS2, RAPSYN, RNF205

Protein Name: 43 kDa receptor-associated protein of the synapse

Molecular Weight: 38kDa

Gene ID: 5913

NCBI Accession: NP_116034

UniProt: Q13702