SCYL2 antibody (C-Term)

Catalog No. ABIN5517315

This Rabbit Polyclonal antibody specifically detects SCYL2 in WB. It exhibits reactivity toward Human, Rat, Cow, Dog, Guinea Pig, Horse, Pig and Rabbit.

Quick Overview for SCYL2 antibody (C-Term) (ABIN5517315)

Target: SCYL2 (SCY1-Like 2 (SCYL2))

Reactivity: Human, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SCYL2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SCYL2 Antibody

Binding Specificity: C-Term

Purpose: SCYL2 Antibody - C-terminal region

Sequence: DLLTGSESEN KEDGLQNKHK RASLTLEEKQ KLAKEQEQAQ KLKSQQPLKP

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Pig: 100%, Rabbit: 92%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against SCYL2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human SCYL2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP73378-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for SCYL2

Target: SCYL2 (SCY1-Like 2 (SCYL2))

Alternative Name: SCYL2

Background:

Background Information: SCYL2 is a component of AP2-containing clathrin coated structures at the plasma membrane or of endocytic coated vesicles. According to PubMed:15809293, it is a probable serine/threonine-protein kinase that phosphorylates, in vitro, the beta2-subunit of the plasma membrane adapter complex AP2 and other proteins in presence of poly-L- lysine. According to PubMed:16914521, it has no detectable kinase activity in vitro. It may regulate clathrin-dependent trafficking between the TGN and/or the endosomal system.

Alternative Symbols: AMC4, AMCNACC, CVAK104

Molecular Weight: 102kDa

Gene ID: 55681

NCBI Accession: XP_005269075

UniProt: Q6P3W7