USP46 antibody (Middle Region)

Catalog No. ABIN5517375

This Rabbit Polyclonal antibody specifically detects USP46 in WB. It exhibits reactivity toward Human, Mouse, Rat, Zebrafish (Danio rerio), Rabbit, Horse, Guinea Pig, Goat, Dog and Cow.

Quick Overview for USP46 antibody (Middle Region) (ABIN5517375)

Target: USP46 (Ubiquitin Specific Peptidase 46 (USP46))

Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Rabbit, Horse, Guinea Pig, Goat, Dog, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This USP46 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-USP46 Antibody

Binding Specificity: Middle Region

Purpose: USP46 Antibody - middle region

Sequence: RDFSNTETLC SEQKYYCETC CSKQEAQKRM RVKKLPMILA LHLKRFKYME

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 79%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against UBP46. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human UBP46

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP59331-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for USP46

Target: USP46 (Ubiquitin Specific Peptidase 46 (USP46))

Alternative Name: USP46

Background:

Background Information: Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating enzymes. USP46 belongs to a large family of cysteine proteases that function as deubiquitinating enzymes (Quesada et al., 2004 [PubMed 14715245]).[supplied by OMIM, Jun 2009]

Gene Name: ubiquitin specific peptidase 46

Protein Name: ubiquitin carboxyl-terminal hydrolase 46

Molecular Weight: 38kDa

Gene ID: 64854

UniProt: P62068