TXNDC12 antibody (N-Term)

Catalog No. ABIN5517454

The Rabbit Polyclonal anti-TXNDC12 antibody is suitable to detect TXNDC12 in samples from Human. It has been validated for WB.

Quick Overview for TXNDC12 antibody (N-Term) (ABIN5517454)

Target: TXNDC12 (Thioredoxin Domain Containing 12 (Endoplasmic Reticulum) (TXNDC12))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TXNDC12 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TXNDC12 Antibody

Binding Specificity: N-Term

Purpose: TXNDC12 Antibody - N-terminal region

Sequence: METRPRLGAT CLLGFSFLLL VISSDGHNGL GKGFGDHIHW RTLEDGKKEA

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TXNDC12

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP78544-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for TXNDC12

Target: TXNDC12 (Thioredoxin Domain Containing 12 (Endoplasmic Reticulum) (TXNDC12))

Alternative Name: TXNDC12

Background:

Background Information: This gene encodes a member of the thioredoxin superfamily. Members of this family are characterized by a conserved active motif called the thioredoxin fold that catalyzes disulfide bond formation and isomerization. This protein localizes to the endoplasmic reticulum and has a single atypical active motif. The encoded protein is mainly involved in catalyzing native disulfide bond formation and displays activity similar to protein-disulfide isomerases. This protein may play a role in defense against endoplasmic reticulum stress. Alternate splicing results in both coding and non-coding variants.

Gene Name: thioredoxin domain containing 12 (endoplasmic reticulum)

Alternative Symbols: AG1, AGR1, ERP16, ERP18, ERP19, TLP19, hAG-1, PDIA16, hTLP19

Protein Name: thioredoxin domain-containing protein 12

Molecular Weight: 18 kDa

Gene ID: 51060

NCBI Accession: NP_056997

UniProt: O95881

Pathways: Cell RedoxHomeostasis