UVSSA/KIAA1530 antibody (C-Term)
Quick Overview for UVSSA/KIAA1530 antibody (C-Term) (ABIN5517486)
Target
See all UVSSA/KIAA1530 (UVSSA) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- C-Term
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Sequence
- GQDLGSSRYS GKGRGKKRRY PSLTNLKAQA DTARARIGRK VFAKAAVRRV
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Predicted Reactivity
- Human: 100%
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Characteristics
- This is a rabbit polyclonal antibody against UVSSA. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human UVSSA
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- UVSSA/KIAA1530 (UVSSA) (UV Stimulated Scaffold Protein A (UVSSA))
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Alternative Name
- UVSSA
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Background
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The protein encoded by this gene appears to be involved in ubiquitination and dephosphorylation of RNA polymerase II subunits that stall after UV irradiation. The encoded protein interacts with several members of the nucleotide excision repair complex to help repair UV-induced DNA damage. Defects in this gene can cause UV-sensitive syndrome 3.
Alias Symbols: UVSSA, KIAA1530,
Protein Interaction Partner: SIRT1, SETD1A, USP7, GTF2H1, ERCC3, ERCC2, DDB1, ERCC8, CDK7, UBC,
Protein Size: 709 -
Gene ID
- 57654
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NCBI Accession
- XP_006713960
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UniProt
- Q2YD98
Target
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