SRGAP2 antibody (N-Term)

Catalog No. ABIN5517501

This Rabbit Polyclonal antibody specifically detects SRGAP2 in WB. It exhibits reactivity toward Human.

Quick Overview for SRGAP2 antibody (N-Term) (ABIN5517501)

Target: SRGAP2 (SLIT-ROBO rho GTPase Activating Protein 2 (SRGAP2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SRGAP2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SRGAP2 Antibody

Binding Specificity: N-Term

Sequence: AERFLAKTCS TKDQQFKKDQ NVLSPVNCWN LLLNQVKRES RDHTTLSDIY

Predicted Reactivity: Cow: 87%, Dog: 100%, Guinea Pig: 87%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 87%

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SRGAP2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SRGAP2

Target: SRGAP2 (SLIT-ROBO rho GTPase Activating Protein 2 (SRGAP2))

Alternative Name: SRGAP2

Background: This locus encodes a member of the SLIT-ROBO Rho GTPase activating protein family. The encoded protein stimulates GTPase activity of Rac1, and plays a role in cortical neuron development. This locus has several paralogs on human chromosome 1 resulting from segmental duplication. While this locus itself is conserved among various species, the paralogs are found only in the genus Homo, and not in the genomes of non-human great apes. Alternatively spliced transcript variants have been described for this locus.

Alias Symbols: FNBP2, SRGAP3, SRGAP2A, ARHGAP34

Protein Interaction Partner: UBC, PPP2R1A, YWHAB, YWHAE, UBD, FASLG, HERC2, EXOC1, DISC1, YWHAG, MYO1G, YLPM1, ATAD3A, ITSN2, SLC25A12, WIPF1, WAS, DIAPH1, ROBO1,

Protein Size: 459

Gene ID: 23380

NCBI Accession: NM_001170637, NP_001258799

UniProt: P0DJJ0