TRMT61B antibody (C-Term)

Catalog No. ABIN5517550

The Rabbit Polyclonal anti-TRMT61B antibody is suitable to detect TRMT61B in samples from Human, Cow, Guinea Pig, Horse, Pig and Rat. It has been validated for WB.

Quick Overview for TRMT61B antibody (C-Term) (ABIN5517550)

Target: TRMT61B (tRNA Methyltransferase 61 (TRMT61B))

Reactivity: Human, Cow, Guinea Pig, Horse, Pig, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRMT61B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TRMT61B Antibody

Binding Specificity: C-Term

Purpose: TRMT61B Antibody - C-terminal region

Sequence: SKINTDVQLD SQEKIGVKGE LFQEDDHEES HSDFPYGSFP YVARPVHWQP

Predicted Reactivity: Cow: 100%, Guinea Pig: 80%, Horse: 93%, Human: 100%, Pig: 86%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against TRMT61B. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human TRMT61B

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP48815-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for TRMT61B

Target: TRMT61B (tRNA Methyltransferase 61 (TRMT61B))

Alternative Name: TRMT61B

Background:

Background Information: TRMT61B is a methyltransferase that catalyzes the formation of N(1)- methyladenine at position 58 (m1A58) in various tRNAs in mitochondrion, including tRNA(Leu) (decephering codons UUA or UUG), tRNA(Lys) and tRNA(Ser) (decephering codons UCA, UCU, UCG or UCC).

Gene Name: tRNA methyltransferase 61 homolog B (S. cerevisiae)

Alternative Symbols: TRMT61B,

Protein Name: Potential tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61B

Molecular Weight: 52kDa

Gene ID: 55006

NCBI Accession: NP_060380

UniProt: Q9BVS5