UBXN1 antibody (N-Term)
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- Target See all UBXN1 Antibodies
- UBXN1 (UBX Domain Protein 1 (UBXN1))
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Binding Specificity
- N-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This UBXN1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- GRAEKALALT GNQGIEAAMD WLMEHEDDPD VDEPLETPLG HILGREPTSS
- Characteristics
- This is a rabbit polyclonal antibody against UBXN1. It was validated on Western Blot.
- Purification
- Affinity purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human UBXN1
- Top Product
- Discover our top product UBXN1 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- UBXN1 (UBX Domain Protein 1 (UBXN1))
- Alternative Name
- UBXN1 (UBXN1 Products)
- Synonyms
- 2B28 antibody, SAKS1 antibody, UBXD10 antibody, 4930455J02Rik antibody, D19Ertd721e antibody, T25529 antibody, RGD1309471 antibody, fb49a05 antibody, wu:fb49a05 antibody, zgc:77531 antibody, UBX domain protein 1 antibody, UBXN1 antibody, Ubxn1 antibody, ubxn1 antibody
- Background
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UBXN1 is a ubiquitin-binding protein that interacts with the BRCA1- BARD1 heterodimer, and regulates its activity. It specifically binds 'Lys-6'-linked polyubiquitin chains. Interaction with autoubiquitinated BRCA1,it leads to inhibit the E3 ubiquitin-protein ligase activity of the BRCA1-BARD1 heterodimer. It is a component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulum that are retrotranslocated in the cytosol.
Alias Symbols: UBXN1, SAKS1,
Protein Interaction Partner: UBXN1, UBQLN1, FAM189A2, PLAA, TRIM39, VCP, UBE2I, UBC, PLA2G4A, MAVS, NSFL1C, STK26, TRNT1, MCTS1, TWF2, PROSC, BASP1, DENR, YWHAE, TXNRD1, TUFM, TUBB2A, PAFAH1B1, HSPA5, HMGB3, HK1, CTPS1, CAPN2, CD81, CSE1L, CLNS1A, ATP6V1A, SSSCA1, USP34, SEC22B, VPS4
Protein Size: 297 - Gene ID
- 51035
- UniProt
- Q04323
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