GLYR1 antibody (N-Term)

Catalog No. ABIN5517597

This Rabbit Polyclonal antibody specifically detects GLYR1 in WB. It exhibits reactivity toward Human.

Quick Overview for GLYR1 antibody (N-Term) (ABIN5517597)

Target: GLYR1 (Glyoxylate Reductase 1 Homolog (GLYR1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GLYR1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GLYR1 Antibody

Binding Specificity: N-Term

Purpose: GLYR1 Antibody - N-terminal region

Sequence: SSHNSSDDKN RRNSSEERSR PNSGDEKRKL SLSEGKVKKN MGEGKKRVSS

Characteristics: This is a rabbit polyclonal antibody against GLYR1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human GLYR1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP73442-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for GLYR1

Target: GLYR1 (Glyoxylate Reductase 1 Homolog (GLYR1))

Alternative Name: GLYR1

Background:

Background Information: GLYR1 may have oxidoreductase activity. It regulates p38 MAP kinase activity by mediating stress activation of p38alpha/MAPK14 and specifically regulating MAPK14 signaling. It indirectly promotes phosphorylation of MAPK14 and activation of ATF2. The phosphorylation of MAPK14 requires upstream activity of MAP2K4 and MAP2K6. It is recruited on chromatin, recognizes and binds trimethylated 'Lys-36' of histone H3 (H3K36me3).

Alternative Symbols: NP60, hNDF, BM045, HIBDL, N-PAC

Molecular Weight: 53kDa

Gene ID: 84656

UniProt: Q49A26