OLFML3 antibody (N-Term)

Catalog No. ABIN5517620

The Rabbit Polyclonal anti-OLFML3 antibody (ABIN5517620) specifically detects OLFML3 in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit and Guinea Pig samples.

Quick Overview for OLFML3 antibody (N-Term) (ABIN5517620)

Target: OLFML3 (Olfactomedin-Like 3 (OLFML3))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OLFML3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-OLFML3 Antibody

Binding Specificity: N-Term

Purpose: OLFML3 Antibody - N-terminal region

Sequence: WSGPLQGQQH HLVEYMERRL AALEERLAQC QDQSSRHAAE LRDFKNKMLP

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against OLFML3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human OLFML3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP48076-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for OLFML3

Target: OLFML3 (Olfactomedin-Like 3 (OLFML3))

Alternative Name: OLFML3

Background:

Background Information: OLFML3 is a secreted scaffold protein that plays an essential role in dorsoventral patterning during early development. It stabilizes axial formation by restricting chordin (CHRD) activity on the dorsal side. Acts by facilitating the association between the tolloid proteases and their substrate chordin (CHRD), leading to enhance chordin (CHRD) degradation. It may have matrix-related function involved in placental and embryonic development, or play a similar role in other physiological processes.

Gene Name: olfactomedin-like 3

Alternative Symbols: OLF44, HNOEL-iso

Protein Name: Olfactomedin-like protein 3

Molecular Weight: 44kDa

Gene ID: 56944

NCBI Accession: NP_064575

UniProt: Q9NRN5