TLL1 antibody (N-Term)

Catalog No. ABIN5517642

This Rabbit Polyclonal antibody specifically detects TLL1 in WB. It exhibits reactivity toward Human, Horse, Mouse, Rat and Zebrafish (Danio rerio).

Quick Overview for TLL1 antibody (N-Term) (ABIN5517642)

Target: TLL1 (Tolloid-Like 1 (TLL1))

Reactivity: Human, Horse, Mouse, Rat, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TLL1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TLL1 Antibody

Binding Specificity: N-Term

Purpose: TLL1 Antibody - N-terminal region

Sequence: LVWLVASGIV FYGELWVCAG LDYDYTFDGN EEDKTETIDY KDPCKAAVFW

Predicted Reactivity: Horse: 86%, Human: 100%, Mouse: 93%, Rat: 93%, Zebrafish: 91%

Characteristics: This is a rabbit polyclonal antibody against TLL1. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human TLL1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64639-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for TLL1

Target: TLL1 (Tolloid-Like 1 (TLL1))

Alternative Name: TLL1

Background:

Background Information: This gene encodes an astacin-like, zinc-dependent, metalloprotease that belongs to the peptidase M12A family. This protease processes procollagen C-propeptides, such as chordin, pro-biglycan and pro-lysyl oxidase. Studies in mice suggest that this gene plays multiple roles in the development of mammalian heart, and is essential for the formation of the interventricular septum. Allelic variants of this gene are associated with atrial septal defect type 6. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Name: tolloid-like 1

Alternative Symbols: TLL, ASD6

Protein Name: Tolloid-like protein 1

Molecular Weight: 43kDa

Gene ID: 7092

UniProt: O43897