TSPYL5 antibody (N-Term)

Catalog No. ABIN5517669

Product Details anti-TSPYL5 Antibody

Target: TSPYL5 (TSPY-Like 5 (TSPYL5))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TSPYL5 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GRAKARVRPA PDDAPRDPDP SQYQSLGEDT QAAQVQAGAG WGGLEAAASA

Characteristics: This is a rabbit polyclonal antibody against TSPYL5. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human TSPYL5

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TSPYL5

Target: TSPYL5 (TSPY-Like 5 (TSPYL5))

Alternative Name: TSPYL5 (TSPYL5 Products)

Synonyms: 6330530B20 antibody, E130308C19Rik antibody, testis-specific protein, Y-encoded-like 5 antibody, TSPY like 5 antibody, Tspyl5 antibody, TSPYL5 antibody

Background: TSPYL5 is involved in modulation of cell growth and cellular response to gamma radiation probably via regulation of the Akt signaling pathway. It is involved in regulation of p53/TP53. It suppresses p53/TP53 protein levels and promotes its ubiquitination, the function is dependent on USP7 and independent on MDM2. It is proposed to displace p53/TP53 from interaction with USP7.

Alias Symbols: TSPYL5, KIAA1750,

Protein Interaction Partner: UBC, USP7,

Protein Size: 417

Gene ID: 85453

NCBI Accession: NP_277047

UniProt: Q86VY4