TSPYL5 antibody (N-Term)

Catalog No. ABIN5517669

This Rabbit Polyclonal antibody specifically detects TSPYL5 in WB. It exhibits reactivity toward Human.

Quick Overview for TSPYL5 antibody (N-Term) (ABIN5517669)

Target: TSPYL5 (TSPY-Like 5 (TSPYL5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TSPYL5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TSPYL5 Antibody

Binding Specificity: N-Term

Purpose: TSPYL5 Antibody - N-terminal region

Sequence: GRAKARVRPA PDDAPRDPDP SQYQSLGEDT QAAQVQAGAG WGGLEAAASA

Characteristics: This is a rabbit polyclonal antibody against TSPYL5. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human TSPYL5

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP73205-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for TSPYL5

Target: TSPYL5 (TSPY-Like 5 (TSPYL5))

Alternative Name: TSPYL5

Background:

Background Information: TSPYL5 is involved in modulation of cell growth and cellular response to gamma radiation probably via regulation of the Akt signaling pathway. It is involved in regulation of p53/TP53. It suppresses p53/TP53 protein levels and promotes its ubiquitination, the function is dependent on USP7 and independent on MDM2. It is proposed to displace p53/TP53 from interaction with USP7.

Alternative Symbols: TSPYL5, KIAA1750,

Molecular Weight: 45kDa

Gene ID: 85453

NCBI Accession: NP_277047

UniProt: Q86VY4