CLN5 antibody (C-Term)

Catalog No. ABIN5517800

The Rabbit Polyclonal anti-CLN5 antibody (ABIN5517800) specifically detects CLN5. The antibody is reactive with Human, Rat, Cow, Dog, Guinea Pig, Horse, Pig and Rabbit samples.

Quick Overview for CLN5 antibody (C-Term) (ABIN5517800)

Target: CLN5 (Ceroid-Lipofuscinosis, Neuronal 5 (CLN5))

Reactivity: Human, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLN5 antibody is un-conjugated

Application: Please inquire

Product Details anti-CLN5 Antibody

Binding Specificity: C-Term

Purpose: CLN5 Antibody - C-terminal region

Sequence: DNETGIYYET WNVKASPEKG AETWFDSYDC SKFVLRTFNK LAEFGAEFKN

Predicted Reactivity: Cow: 77%, Dog: 79%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Pig: 86%, Rabbit: 86%, Rat: 79%

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CLN5

Application Details

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP59986-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for CLN5

Target: CLN5 (Ceroid-Lipofuscinosis, Neuronal 5 (CLN5))

Alternative Name: CLN5

Background:

Background Information: This gene is one of eight which have been associated with neuronal ceroid lipofuscinoses (NCL). Also referred to as Batten disease, NCL comprises a class of autosomal recessive, neurodegenerative disorders affecting children. The genes responsible likely encode proteins involved in the degradation of post-translationally modified proteins in lysosomes. The primary defect in NCL disorders is thought to be associated with lysosomal storage function.

Gene Name: ceroid-lipofuscinosis, neuronal 5

Alternative Symbols: NCL

Protein Name: ceroid-lipofuscinosis neuronal protein 5

Molecular Weight: 39 kDa

Gene ID: 1203

NCBI Accession: NP_006484

UniProt: O75503