CLN5 antibody (C-Term)

Catalog No. ABIN5517800

Product Details anti-CLN5 Antibody

Target: CLN5 (Ceroid-Lipofuscinosis, Neuronal 5 (CLN5))

Binding Specificity: C-Term

Reactivity: Human, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLN5 antibody is un-conjugated

Application: Please inquire

Sequence: DNETGIYYET WNVKASPEKG AETWFDSYDC SKFVLRTFNK LAEFGAEFKN

Predicted Reactivity: Cow: 77%, Dog: 79%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Pig: 86%, Rabbit: 86%, Rat: 79%

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CLN5

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CLN5

Target: CLN5 (Ceroid-Lipofuscinosis, Neuronal 5 (CLN5))

Alternative Name: CLN5 (CLN5 Products)

Synonyms: NCL antibody, A730075N08Rik antibody, CLN5, intracellular trafficking protein antibody, ceroid-lipofuscinosis, neuronal 5 antibody, CLN5 antibody, Cln5 antibody

Background: This gene is one of eight which have been associated with neuronal ceroid lipofuscinoses (NCL). Also referred to as Batten disease, NCL comprises a class of autosomal recessive, neurodegenerative disorders affecting children. The genes responsible likely encode proteins involved in the degradation of post-translationally modified proteins in lysosomes. The primary defect in NCL disorders is thought to be associated with lysosomal storage function.

Alias Symbols: NCL

Protein Interaction Partner: ARHGAP36, FBXO27, SPNS1, SFXN3, SLC25A22, SEC61A1, FBXO6, PHGDH, GANAB, OS9, CDIPT, SLC25A13, CDS2, SLC25A11, XPO1, SLC25A1, SEL1L, RPN1, RCN2, HMGCS1, DBH, CLN5, CLGN, CANX, CALU, CALR, ATP2A2, ATP1A3, ARF4, SLC25A6, SLC25A5, SLC25A4, Dlg4, UBC, KRT8,

Protein Size: 358

Gene ID: 1203

NCBI Accession: NM_006493, NP_006484

UniProt: O75503