DENND5B antibody (Middle Region)

Catalog No. ABIN5517986

The Rabbit Polyclonal anti-DENND5B antibody (ABIN5517986) specifically detects DENND5B in WB. The antibody is reactive with Human, Mouse, Cow, Dog, Guinea Pig, Horse, Rabbit, Rat and Zebrafish (Danio rerio) samples.

Quick Overview for DENND5B antibody (Middle Region) (ABIN5517986)

Target: DENND5B (DENN/MADD Domain Containing 5B (DENND5B))

Reactivity: Human, Mouse, Cow, Dog, Guinea Pig, Horse, Rabbit, Rat, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DENND5B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DENND5B Antibody

Binding Specificity: Middle Region

Purpose: DENND5B Antibody - middle region

Sequence: ILPASLLHFL DAPVPYLMGL QSKEGTDRSK LELPQEANLC FVDIDNHFIE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against DENND5B. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human DENND5B

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP52769-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for DENND5B

Target: DENND5B (DENN/MADD Domain Containing 5B (DENND5B))

Alternative Name: DENND5B

Background:

Background Information: DENND5B is a guanine nucleotide exchange factor (GEF) which may activate RAB39A and/or RAB39B. It promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form.

Gene Name: DENN/MADD domain containing 5B

Alternative Symbols: DENND5B,

Protein Name: DENN domain-containing protein 5B

Molecular Weight: 55kDa

Gene ID: 160518

UniProt: Q6ZUT9