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DENND3 antibody (C-Term)

DENND3 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN5518005
  • Target See all DENND3 products
    DENND3 (DENN/MADD Domain Containing 3 (DENND3))
    Binding Specificity
    C-Term
    Reactivity
    • 1
    • 1
    • 1
    Human
    Host
    • 2
    Rabbit
    Clonality
    • 2
    Polyclonal
    Conjugate
    • 2
    This DENND3 antibody is un-conjugated
    Application
    • 2
    • 1
    Western Blotting (WB)
    Sequence
    INCMIRVKKQ VWVGSRGLGQ GTPKGKIYVI DAERKTVEKE LVAHMDTVRT
    Characteristics
    This is a rabbit polyclonal antibody against DENND3. It was validated on Western Blot.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C-terminal region of Human DENND3
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    DENND3 (DENN/MADD Domain Containing 3 (DENND3))
    Alternative Name
    DENND3 (DENND3 Products)
    Synonyms
    AI447457 antibody, E030003N15Rik antibody, DENN domain containing 3 antibody, DENN/MADD domain containing 3 antibody, DENND3 antibody, Dennd3 antibody
    Background
    DENND3 is a guanine nucleotide exchange factor (GEF) activating RAB12. It promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB12 into its active GTP-bound form. Thereby, DENND3 may play a role in protein transport from recycling endosomes to lysosomes regulating, for instance, the degradation of the transferrin receptor.

    Alias Symbols: DENND3, KIAA0870,

    Protein Interaction Partner: UBC, YAP1,

    Protein Size: 1146
    Gene ID
    22898
    NCBI Accession
    NP_055772
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